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Michael Corvin (Scott Speedman) is a medical student who is heading home after a long day of school and work when he unexpectedly finds himself in the middle of what appears to be a rumble between two well turned-out street gangs. What Michael doesn't know is he has witnessed a skirmish between two deadly underground communities, unknown to the mortal world, who are battling for supremacy, the Death Dealers, a tribe of vampires, and the Lycans, a band of werewolves. Selene (Kate Beckinsale) is a leading member of the Death Dealers who hears through the grapevine that the Lycans have plans to capture the aspiring doctor who witnessed their battle. She is convinced that the Lycans are planning a major attack against the Death Dealers, although vampire kingpin Kraven (Shane Brolly) is certain she's crediting the Lycans with more intelligence than they can muster. As Selene shadows Michael, he's attacked by Lucian (Michael Sheen), the leader of the werewolf community, and the man she wants to save has now become a sworn enemy.
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